1887043-58-4
1887043-58-4
Chemical Structure
5-HT7R antagonist 3
- CAS No.: 1887043-58-4
- Formula:C30H33FN4O3
- Molecular Weight:516.61
InChIKey: NPUZJIOVBIDKGO-VIZCGCQYSA-N
SMILES: O=C1N(C[C@H](O)CN2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C([C@](C)(C5=CC=C(F)C=C5)N1)=O
Biological Activity: 5-HT7R antagonist 3 (Compound 6.4) is a selective 5-HT7R antagonist (Ki: 8 nM), with Ki of 511 nM (D2), 8930 nM (5-HT1A) and 5786 nM (5-HT2A), respectively. 5-HT7R antagonist 3 possesses antidepressant and anxiolytic effects in mice[1].
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5-HT7R antagonist 3 | 5-HT7R antagonist 3 (Compound 6.4) is a selective 5-HT7R antagonist (Ki: 8 nM), with Ki of 511 nM (D2), 8930 nM (5-HT1A) and 5786 nM (5-HT2A), respectively. 5-HT7R antagonist 3 possesses antidepressant and anxiolytic effects in mice. | |||||||||||||||||||||
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References
Keywords
