202815-17-6
Chemical Structure
NY-ESO-1 (157-165) peptide
- CAS No.: 202815-17-6
- Formula:C49H79N11O13S2
- Molecular Weight:1094.35
InChIKey: VUKKCKFBCXDRLN-NVAXFOGYSA-N
SMILES: O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
Biological Activity: NY-ESO-1 (157-165) peptide is a peptide fragment from NY-ESO-1 protein. NY-ESO-1 (157-165) peptide can activate the immune system, especially for HLA-A2 positive individuals, it can be recognized by CD8+ T cells, thus triggering an immune response. NY-ESO-1 (157-165) peptide is expressed in a variety of tumors and can be used as a target for tumor immunotherapy[1][2].
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NY-ESO-1 (157-165) peptide | 99.75% | NY-ESO-1 (157-165) peptide is a peptide fragment from NY-ESO-1 protein. NY-ESO-1 (157-165) peptide can activate the immune system, especially for HLA-A2 positive individuals, it can be recognized by CD8+ T cells, thus triggering an immune response. NY-ESO-1 (157-165) peptide is expressed in a variety of tumors and can be used as a target for tumor immunotherapy. | ||||||||||||||||||||
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- [1]. Davis I D, et al. Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans[J]. Proceedings of the National Academy of Sciences, 2004, 101(29): 10697-10702. [Content Brief]
- [2]. Bethune MT, et al. Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10702-E10711. [Content Brief]
Keywords
