NY-ESO-1 (157-165) peptide
Based on 1 Customer Validation
NY-ESO-1 (157-165) peptide is a peptide fragment from NY-ESO-1 protein. NY-ESO-1 (157-165) peptide can activate the immune system, especially for HLA-A2 positive individuals, it can be recognized by CD8+ T cells, thus triggering an immune response. NY-ESO-1 (157-165) peptide is expressed in a variety of tumors and can be used as a target for tumor immunotherapy.
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 202815-17-6
- Formula: C49H79N11O13S2
- Molecular Weight:1094.35
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
NY-ESO-1 (157-165) is a highly immunogenic epitope of NY-ESO-1, which can induce spontaneous or vaccine-induced T cell immune responses[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 202815-17-6
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Appearance Solid
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Molecular Weight 1094.35
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Formula C49H79N11O13S2
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Color White to off-white
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Sequence
Ser-Leu-Leu-Met-Trp-Ile-Thr-Gln-Cys
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Sequence Shortening
SLLMWITQC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (45.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Davis I D, et al. Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans[J]. Proceedings of the National Academy of Sciences, 2004, 101(29): 10697-10702. [Content Brief]
[2]. Bethune MT, et al. Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10702-E10711. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9138 mL | 4.5689 mL | 9.1378 mL | 22.8446 mL |
| 5 mM | 0.1828 mL | 0.9138 mL | 1.8276 mL | 4.5689 mL | |
| 10 mM | 0.0914 mL | 0.4569 mL | 0.9138 mL | 2.2845 mL | |
| 15 mM | 0.0609 mL | 0.3046 mL | 0.6092 mL | 1.5230 mL | |
| 20 mM | 0.0457 mL | 0.2284 mL | 0.4569 mL | 1.1422 mL | |
| 25 mM | 0.0366 mL | 0.1828 mL | 0.3655 mL | 0.9138 mL | |
| 30 mM | 0.0305 mL | 0.1523 mL | 0.3046 mL | 0.7615 mL | |
| 40 mM | 0.0228 mL | 0.1142 mL | 0.2284 mL | 0.5711 mL |