2055015-61-5

GLPG2451 Chemical Structure
2055015-61-5

Chemical Structure

GLPG2451

  • CAS No.: 2055015-61-5
  • Formula:C16H16F3N3O5S
  • Molecular Weight:419.38

IUPAC Name: (S)-3-amino-N-(2-hydroxypropyl)-5-((4-(trifluoromethoxy)phenyl)sulfonyl)picolinamide

InChIKey: UMOGNCVNHXWFIX-VIFPVBQESA-N

SMILES: O=S(C1=CC=C(OC(F)(F)F)C=C1)(C2=CN=C(C(NC[C@@H](O)C)=O)C(N)=C2)=O

Biological Activity: GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-119936 		GLPG2451 99.68% GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.
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