2097734-03-5
Chemical Structure
Para-aminoblebbistatin
- CAS No.: 2097734-03-5
- Formula:C18H17N3O2
- Molecular Weight:307.35
IUPAC Name: (S)-1-(4-aminophenyl)-3a-hydroxy-6-methyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
InChIKey: LYWLZINJPRNWFF-GOSISDBHSA-N
SMILES: O=C1[C@@]2(O)C(N(C3=CC=C(N)C=C3)CC2)=NC4=CC=C(C)C=C41
Biological Activity: Para-aminoblebbistatin is the inhibitor for myosin II. Para-aminoblebbistatin inhibits the ATPase activity of myosin II, thereby blocking the formation and contraction of the actin-myosin network. Para-aminoblebbistatin is a non-fluorescent and photostable Blebbistatin (HY-13813) derivative[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Para-aminoblebbistatin | 99.9% | Para-aminoblebbistatin is the inhibitor for myosin II. Para-aminoblebbistatin inhibits the ATPase activity of myosin II, thereby blocking the formation and contraction of the actin-myosin network. Para-aminoblebbistatin is a non-fluorescent and photostable Blebbistatin (HY-13813) derivative. | ||||||||||||||||||||
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- [1]. Várkuti BH, et al. A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative. Sci Rep. 2016 May 31;6:26141. [Content Brief]
- [2]. Képiró M, et al. para-Nitroblebbistatin, the non-cytotoxic and photostable myosin II inhibitor. Angew Chem Int Ed Engl. 2014 Jul 28;53(31):8211-5. [Content Brief]
Keywords
