2131798-12-2
2131798-12-2
Chemical Structure
Ganfeborole
Synonym(s): GSK656 free base; GSK3036656 free base; GSK070 free base
- No. CAS: 2131798-12-2
- Formula:C10H13BClNO4
- Molecular Weight:257.48
IUPAC Name: (S)-3-(aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol
InChIKey: DJUOWOXTPXUHDQ-MRVPVSSYSA-N
SMILES: OB1O[C@H](CN)C2=C(Cl)C=CC(OCCO)=C21
Biological Activity: Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC50 of 0.20 μM. Ganfeborole can be used for the research of tuberculosis[1].
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Ganfeborole | Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC50 of 0.20 μM. Ganfeborole can be used for the research of tuberculosis. | |||||||||||||||||||||
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References
Keywords
