215036-81-0
Chemical Structure
Phenchlobenpyrrone
- CAS No.: 215036-81-0
- Formula:C17H16ClNO
- Molecular Weight:285.77
IUPAC Name: (4R,5R)-5-(2-chlorobenzyl)-4-phenylpyrrolidin-2-one
InChIKey: VKZXZQUFDSNROH-GDBMZVCRSA-N
SMILES: O=C1N[C@@H]([C@H](C1)C2=CC=CC=C2)CC3=CC=CC=C3Cl
Biological Activity: Phenchlobenpyrrone is a highly selective neuronal calcium antagonist that crosses the blood-brain barrier. Phenchlobenpyrrone mildly inhibits AChE activity. Phenchlobenpyrrone inhibits Aβ aggregation and promotes the clearance of Aβ oligomers. Phenchlobenpyrrone reduces abnormal phosphorylation of Tau protein. Phenchlobenpyrrone may be used in research on Alzheimer's disease[1].
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Phenchlobenpyrrone | Phenchlobenpyrrone is a highly selective neuronal calcium antagonist that crosses the blood-brain barrier. Phenchlobenpyrrone mildly inhibits AChE activity. Phenchlobenpyrrone inhibits Aβ aggregation and promotes the clearance of Aβ oligomers. Phenchlobenpyrrone reduces abnormal phosphorylation of Tau protein. Phenchlobenpyrrone may be used in research on Alzheimer's disease. | |||||||||||||||||||||
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Keywords
