2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel Cholinesterase (ChE) Amyloid-β Tau Protein
  4. Phenchlobenpyrrone

Phenchlobenpyrrone is a highly selective neuronal calcium antagonist that crosses the blood-brain barrier. Phenchlobenpyrrone mildly inhibits AChE activity. Phenchlobenpyrrone inhibits Aβ aggregation and promotes the clearance of Aβ oligomers. Phenchlobenpyrrone reduces abnormal phosphorylation of Tau protein. Phenchlobenpyrrone may be used in research on Alzheimer's disease.

For research use only. We do not sell to patients.

Phenchlobenpyrrone

Phenchlobenpyrrone Chemical Structure

CAS No. : 215036-81-0

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Phenchlobenpyrrone Related Antibodies

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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AChE BChE

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Description

Phenchlobenpyrrone is a highly selective neuronal calcium antagonist that crosses the blood-brain barrier. Phenchlobenpyrrone mildly inhibits AChE activity. Phenchlobenpyrrone inhibits Aβ aggregation and promotes the clearance of Aβ oligomers. Phenchlobenpyrrone reduces abnormal phosphorylation of Tau protein. Phenchlobenpyrrone may be used in research on Alzheimer's disease[1].

Molecular Weight

285.77

Formula

C17H16ClNO
CAS No.
SMILES

O=C1N[C@@H]([C@H](C1)C2=CC=CC=C2)CC3=CC=CC=C3Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Phenchlobenpyrrone Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenchlobenpyrrone215036-81-0Calcium ChannelCholinesterase (ChE)Amyloid-βTau ProteinCa2+ channelsCa channelsβ-amyloid peptideAβAbetaAlzheimer's diseaseclinical trialnatural productmulti-target therapycalcium channel antagonistacetylcholinesterase inhibitoramyloid-betatau proteinneuroprotectionInhibitorinhibitorinhibit

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