2315262-28-1
2315262-28-1
Chemical Structure
Sphingosylphosphorylcholine-d9
- CAS No.: 2315262-28-1
- Formula:C23H40D9N2O5P
- Molecular Weight:473.67
IUPAC Name: (2S,3R,E)-3-hydroxy-2-pentadecanamidooctadec-4-en-1-yl (2-(tris(methyl-d3)ammonio)ethyl) phosphate
InChIKey: JLVSPVFPBBFMBE-IQSZTMPESA-N
SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])([O-])=O
Biological Activity: Sphingosylphosphorylcholine-d9 is deuterium labeled Sphingosylphosphorylcholine.
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Sphingosylphosphorylcholine-d9 | 99.0% | Sphingosylphosphorylcholine-d9 is deuterium labeled Sphingosylphosphorylcholine. | ||||||||||||||||||||
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Sphingosylphosphorylcholine-d7 | 99.90% | Sphingosylphosphorylcholine-d7 is the deuterium labeled Sphingosylphosphorylcholine (HY-132187). | ||||||||||||||||||||
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Sphingosylphosphorylcholine | 99.50% | Sphingosylphosphorylcholine is a bioactive lipid and a major component of plasma high-density lipoprotein that binds to OGR1 with a Kd of 33.3 nM. Sphingosylphosphorylcholine triggers delayed phosphorylation of Smad2, upregulates α-SMA expression, and activates TRPM3. Sphingosylphosphorylcholine reduces Apoptosis and upregulates the expression of uPA and its receptor uPA-R. Sphingosylphosphorylcholine exerts anti-apoptotic, anti-cardiac hypertrophy and pro-wound healing effects. Sphingosylphosphorylcholine induces scratching behavior in mice. Sphingosylphosphorylcholine is used in studies related to atopic dermatitis, promyelocytic leukemia, heart failure, myocardial ischemia/reperfusion injury, ovarian cancer, breast cancer, pancreatic cancer, and skin wound healing disorders in genetically impaired healing diabetes. | ||||||||||||||||||||
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