2361418-52-0
Chemical Structure
PI3K/HDAC-IN-1
- CAS No.: 2361418-52-0
- Formula:C22H25FN4O4
- Molecular Weight:428.46
IUPAC Name: 7-((6-(5-fluoro-6-methoxypyridin-3-yl)-4-methylquinazolin-8-yl)oxy)-N-hydroxyheptanamide
InChIKey: BQKQDMVFQZHPJZ-UHFFFAOYSA-N
SMILES: CC1=C2C(C(OCCCCCCC(NO)=O)=CC(C3=CC(F)=C(OC)N=C3)=C2)=NC=N1
Biological Activity: PI3K/HDAC-IN-1 is a potent dual inhibitor of PI3K/HDAC, potently inhibits PI3Kδ and HDAC1 with IC50s of 8.1 nM and 1.4 nM, respectively[1].
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PI3K/HDAC-IN-1 | PI3K/HDAC-IN-1 is a potent dual inhibitor of PI3K/HDAC, potently inhibits PI3Kδ and HDAC1 with IC50s of 8.1 nM and 1.4 nM, respectively. | |||||||||||||||||||||
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Keywords