1. PI3K/Akt/mTOR
    Epigenetics
    Cell Cycle/DNA Damage
  2. PI3K
    HDAC
  3. PI3K/HDAC-IN-1

PI3K/HDAC-IN-1 

Cat. No.: HY-128582
Handling Instructions

PI3K/HDAC-IN-1 is a potent dual inhibitor of PI3K/HDAC, potently inhibits PI3Kδ and HDAC1 with IC50s of 8.1 nM and 1.4 nM, respectively.

For research use only. We do not sell to patients.

PI3K/HDAC-IN-1 Chemical Structure

PI3K/HDAC-IN-1 Chemical Structure

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Description

PI3K/HDAC-IN-1 is a potent dual inhibitor of PI3K/HDAC, potently inhibits PI3Kδ and HDAC1 with IC50s of 8.1 nM and 1.4 nM, respectively[1].

IC50 & Target

PI3Kα

42 nM (IC50)

PI3Kβ

101 nM (IC50)

PI3Kγ

67 nM (IC50)

PI3Kδ

8.1 nM (IC50)

HDAC1

1.4 nM (IC50)

HDAC2

3.0 nM (IC50)

HDAC6

6.6 nM (IC50)

HDAC8

18 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

428.46

Formula

C₂₂H₂₅FN₄O₄

SMILES

CC1=C2C(C(OCCCCCCC(NO)=O)=CC(C3=CC(F)=C(OC)N=C3)=C2)=NC=N1

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
PI3K/HDAC-IN-1
Cat. No.:
HY-128582
Quantity:

PI3K/HDAC-IN-1

Cat. No.: HY-128582