2409825-32-5
2409825-32-5
Chemical Structure
NP3-562
- CAS No.: 2409825-32-5
- Formula:C19H24ClN5O3S
- Molecular Weight:437.94
InChIKey: AXAOJXUYQVCGBD-LLVKDONJSA-N
SMILES: CC(O)(C(N1C2=C(SC(Cl)=C2)C=C13)=NN(CC(N[C@H]4CN(CCC4)C)=O)C3=O)C
Biological Activity: NP3-562 is an orally active NLRP3 Inhibitor. NP3-562 inhibits IL-1β release in the supernatant of Nigericin (HY-127019)-stimulated THP-1 cells (IC50 = 66 nM), human whole blood (IC50 = 214 nM) and a mouse acute peritonitis model. NP3-562 can be used for the study of acute peritonitis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NP3-562 | 98.16% | NP3-562 is an orally active NLRP3 Inhibitor. NP3-562 inhibits IL-1β release in the supernatant of Nigericin (HY-127019)-stimulated THP-1 cells (IC50 = 66 nM), human whole blood (IC50 = 214 nM) and a mouse acute peritonitis model. NP3-562 can be used for the study of acute peritonitis. | ||||||||||||||||||||
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References
Keywords
