2414099-82-2
Chemical Structure
HIV-1 inhibitor-39
- CAS No.: 2414099-82-2
- Formula:C20H17ClN4O4S4
- Molecular Weight:541.09
IUPAC Name: 2-((5-(2-(3-chlorophenyl)-4-oxothiazolidin-3-yl)-1,3,4-thiadiazol-2-yl)thio)-N-(4-(methylsulfonyl)phenyl)acetamide
InChIKey: QFCCQGBVYCZXMZ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(S(=O)(C)=O)C=C1)CSC2=NN=C(N3C(C4=CC=CC(Cl)=C4)SCC3=O)S2
Biological Activity: HIV-1 inhibitor-39 (compound 3c) is a potent HIV-1 inhibitor with an EC50 of >112.88 µM. HIV-1 inhibitor-39 shows anti-RT (HIV-1 reverse transcriptase) activities with an IC50 of 15.75 µM. HIV-1 inhibitor-39 shows cytotoxicity for MT-4 cells with an CC50 of 112.9 µM[1].
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HIV-1 inhibitor-39 | HIV-1 inhibitor-39 (compound 3c) is a potent HIV-1 inhibitor with an EC50 of >112.88 µM. HIV-1 inhibitor-39 shows anti-RT (HIV-1 reverse transcriptase) activities with an IC50 of 15.75 µM. HIV-1 inhibitor-39 shows cytotoxicity for MT-4 cells with an CC50 of 112.9 µM. | |||||||||||||||||||||
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Keywords
