2416941-68-7
Chemical Structure
HMG499
- CAS No.: 2416941-68-7
- Formula:C33H54O3
- Molecular Weight:498.78
IUPAC Name: (3S,7R,8S,9S,10R,13R,14S,17R)-17-((R)-6-allyl-6-hydroxynon-8-en-2-yl)-4,4,10,13-tetramethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
InChIKey: LPLLZSOEZAVGBO-XHBYIXHHSA-N
SMILES: C[C@H](CCCC(CC=C)(CC=C)O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C=C4C(C)(C)[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Activity: HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HMG499 | 96.12% | HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis. | ||||||||||||||||||||
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Keywords