2417718-25-1
2417718-25-1
Chemical Structure
VT104
- CAS No.: 2417718-25-1
- Formula:C25H19F3N2O
- Molecular Weight:420.43
IUPAC Name: (S)-N-(1-(pyridin-2-yl)ethyl)-5-(4-(trifluoromethyl)phenyl)-2-naphthamide
InChIKey: AAZUPSFRSHFTGV-INIZCTEOSA-N
SMILES: O=C(C1=CC=C2C(C3=CC=C(C(F)(F)F)C=C3)=CC=CC2=C1)N[C@H](C4=NC=CC=C4)C
Biological Activity: VT104 is a potent and orally active YAP/TAZ inhibitor. VT104 prevents palmitoylation of endogenous TEAD1 and TEAD3 proteins. VT104 can be used in research of cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VT104 | 99.94% | VT104 is a potent and orally active YAP/TAZ inhibitor. VT104 prevents palmitoylation of endogenous TEAD1 and TEAD3 proteins. VT104 can be used in research of cancer. | ||||||||||||||||||||
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References
- [1]. Tang TT, et, al. Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. Mol Cancer Ther. 2021 Jun;20(6):986-998. [Content Brief]
- [2]. Barry ER, et, al. Recent Therapeutic Approaches to Modulate the Hippo Pathway in Oncology and Regenerative Medicine. Cells. 2021 Oct 11;10(10):2715. [Content Brief]
Keywords
