2419358-87-3
2419358-87-3
Chemical Structure
PI5P4Kγ-IN-1
- CAS No.: 2419358-87-3
- Formula:C20H20N4O
- Molecular Weight:332.40
InChIKey: VGFHPNRWHOQLEB-UHFFFAOYSA-N
SMILES: NC1=NC(C2=C(CCC3)NC4=C2C=C(C5=CCOCC5)C=C4)=C3C=N1
Biological Activity: PI5P4Kγ-IN-1 is an ATP-competitive, highly selective chemical probe for PI5P4Kγ, with a Kd of 19 nM and an IC50 of 67 nM. PI5P4Kγ-IN-1 effectively inhibits PI5P4Kγ function and activates the mTORC1 signaling pathway in cells. PI5P4Kγ-IN-1 can be used in studies related to diseases such as breast cancer[1].
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PI5P4Kγ-IN-1 | 98.82% | PI5P4Kγ-IN-1 is an ATP-competitive, highly selective chemical probe for PI5P4Kγ, with a Kd of 19 nM and an IC50 of 67 nM. PI5P4Kγ-IN-1 effectively inhibits PI5P4Kγ function and activates the mTORC1 signaling pathway in cells. PI5P4Kγ-IN-1 can be used in studies related to diseases such as breast cancer. | ||||||||||||||||||||
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References
Keywords
