2421120-96-7
2421120-96-7
Chemical Structure
AChE/BChE-IN-8
- CAS No.: 2421120-96-7
- Formula:C26H32N2O2
- Molecular Weight:404.54
IUPAC Name: 1-(6-(benzylamino)hexyl)-3-(benzyloxy)-2-methylpyridin-4(1H)-one
InChIKey: UIAHSQRUFROBRQ-UHFFFAOYSA-N
SMILES: CC1=C(C(C=CN1CCCCCCNCC2=CC=CC=C2)=O)OCC3=CC=CC=C3
Biological Activity: AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor with Ki values of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 can cross the BBB and has low cytotoxicity[1].
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AChE/BChE-IN-8 | AChE/BChE-IN-8 (Compound 5a) is an uncompetitive AChE and mixed BChE inhibitor with Ki values of 0.788 μM and 2.364 μM against Electrophorus electricus AChE (EeAChE) and equine BChE (eqBChE), respectively. AChE/BChE-IN-8 can cross the BBB and has low cytotoxicity. | |||||||||||||||||||||
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References
Keywords
