2454133-88-9
Chemical Structure
Antitumor agent-70
- CAS No.: 2454133-88-9
- Formula:C21H18N4O2
- Molecular Weight:358.39
IUPAC Name: (E)-4-((2-nicotinoylhydrazono)methyl)-N-(p-tolyl)benzamide
InChIKey: IXYMMBYRNJWPSX-YDZHTSKRSA-N
SMILES: O=C(C1=CC=CN=C1)N/N=C/C2=CC=C(C(NC3=CC=C(C)C=C3)=O)C=C2
Biological Activity: Antitumor agent-70 (compound 8b) has anti-tumor activity and can induce cell apoptosis. Antitumor agent-70 inhibits multiple myeloma with an IC50 value of 0.12 μM. Antitumor agent-70 is a potential multi-targeted kinase inhibitor especially for c-Kit[1].
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Antitumor agent-70 | Antitumor agent-70 (compound 8b) has anti-tumor activity and can induce cell apoptosis. Antitumor agent-70 inhibits multiple myeloma with an IC50 value of 0.12 μM. Antitumor agent-70 is a potential multi-targeted kinase inhibitor especially for c-Kit. | |||||||||||||||||||||
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Keywords