2483736-09-8
2483736-09-8
Chemical Structure
Sodium α-ketoisocaproic acid-13C2
Synonym(s): Sodium 4-methyl-2-oxopentanoate-13C2; 2-Ketoisocaproic acid-13C2 sodium salt
- CAS No.: 2483736-09-8
- Formula:C413C2H10O3
- Molecular Weight:132.13
IUPAC Name: pyridin-3-ylmethyl (4-((2-(3-(2-aminophenyl)ureido)phenyl)carbamoyl)benzyl)carbamate
InChIKey: BKAJNAXTPSGJCU-MPOCSFTDSA-N
SMILES: CC(C)C[13C]([13C](O)=O)=O
Biological Activity: Sodium α-ketoisocaproic acid-13C2 is the 13C labeled Sodium α-ketoisocaproic acid[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sodium α-ketoisocaproic acid-13C2 | 99.95% | Sodium α-ketoisocaproic acid-13C2 is the 13C labeled Sodium α-ketoisocaproic acid. | ||||||||||||||||||||
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4-Methyl-2-oxopentanoic acid (Standard) | 95.67% | 4-Methyl-2-oxopentanoic acid (Standard) is the analytical standard of 4-Methyl-2-oxopentanoic acid. This product is intended for research and analytical applications. 4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid), an abnormal metabolite, is both a neurotoxin and a metabotoxin. | ||||||||||||||||||||
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4-Methyl-2-oxopentanoic acid | 98.49% | 4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid also causes oxidative damage, leading to cognitive deficits, inhibits α-ketoglutarate dehydrogenase activity, acts as an oxidative phosphorylation uncoupler and metabolic inhibitor. 4-Methyl-2-oxopentanoic acid acts as a nutrient signal and stimulates skeletal muscle protein synthesis. 4-Methyl-2-oxopentanoic acid can be used in the study of maple syrup urine disease. | ||||||||||||||||||||
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References
