2497485-14-8
2497485-14-8
Chemical Structure
Ad-JQ1
- CAS No.: 2497485-14-8
- Formula:C37H47ClN6O4S
- Molecular Weight:707.32
SMILES: O=C(NCCOCCOCCNC(C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1)=O)CC5(C[C@@H](C6)C7)C[C@@H]7C[C@@H]6C5
Biological Activity: Ad-JQ1 (Compound 16) is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for BRD4 (HY-78695) and a PROTAC linker (HY-176390), which recruits E3 ligases. Ad-JQ1 can be used for synthesis of PROTAC β-NF-JQ1 (HY-130256)[1].
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Ad-JQ1 | Ad-JQ1 (Compound 16) is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for BRD4 (HY-78695) and a PROTAC linker (HY-176390), which recruits E3 ligases. Ad-JQ1 can be used for synthesis of PROTAC β-NF-JQ1 (HY-130256). | |||||||||||||||||||||
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References
Keywords
