2498762-42-6
Chemical Structure
Antitubercular agent-32
- CAS No.: 2498762-42-6
- Formula:C22H28N4O5S2
- Molecular Weight:492.61
IUPAC Name: 2-(4-(cyclohexylmethyl)-4,7-diazaspiro[2.5]octan-7-yl)-6-(methylsulfonyl)-8-nitro-4H-benzo[e][1,3]thiazin-4-one
InChIKey: WDMGWMXNDMKIHQ-UHFFFAOYSA-N
SMILES: CS(=O)(C(C=C12)=CC([N+]([O-])=O)=C1SC(N(CCN3CC4CCCCC4)CC53CC5)=NC2=O)=O
Biological Activity: Antitubercular agent-32 is a derivate of Benzothiazinone (HY-13579A), inhibits M. tuberculosis, and shows improved metabolic stability and enhanced water solubility. Antitubercular agent-32 exerts antitubercular effect by targeting decaprenylphosphoryl-β-D-ribose 2’-oxidase (DprE1, IC50=3.9 μM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Antitubercular agent-32 | Antitubercular agent-32 is a derivate of Benzothiazinone (HY-13579A), inhibits M. tuberculosis, and shows improved metabolic stability and enhanced water solubility. Antitubercular agent-32 exerts antitubercular effect by targeting decaprenylphosphoryl-β-D-ribose 2’-oxidase (DprE1, IC50=3.9 μM). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
