2522666-80-2
Chemical Structure
DNA Gyrase-IN-2
- CAS No.: 2522666-80-2
- Formula:C24H24N8OS2
- Molecular Weight:504.63
IUPAC Name: (Z)-2-(2-((Z)-2-(2-((Z)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylidene)hydrazinyl)thiazol-4(5H)-ylidene)hydrazinyl)-5-(2-(p-tolyl)hydrazono)thiazol-4(5H)-one
InChIKey: QTHOIANZRFHEBM-PSKUCGQESA-N
SMILES: O=C1N=C(N/N=C2N=C(N/N=C3CCCCC4=CC=CC=C4/3)SC\2)S/C1=N\NC5=CC=C(C)C=C5
Biological Activity: DNA Gyrase-IN-2 (Compound 22a) is a bacterial DNA gyrase B inhibitor with IC50s of 3.29-10.49 and 4.41-5.61 µM for E. coli DNA gyrase and M. tuberculosis DNA gyrase. Anti-tubercular and antibacterial activity[1].
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DNA Gyrase-IN-2 | DNA Gyrase-IN-2 (Compound 22a) is a bacterial DNA gyrase B inhibitor with IC50s of 3.29-10.49 and 4.41-5.61 µM for E. coli DNA gyrase and M. tuberculosis DNA gyrase. Anti-tubercular and antibacterial activity. | |||||||||||||||||||||
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Keywords
