2639542-32-6
Chemical Structure
CDK5-IN-3
- CAS No.: 2639542-32-6
- Formula:C22H26N4O
- Molecular Weight:362.47
IUPAC Name: 7-((4-(((4,4-difluorobutyl)(methyl)amino)methyl)benzyl)oxy)-4-(hydroxymethyl)-2H-chromen-2-one
InChIKey: MLZPRAPIZUZUNO-JOCHJYFZSA-N
SMILES: C[C@@](C1=CC=C2C(C=C(NC3=CC=CC=C3)N=C2)=N1)(O)C4CCN(C)CC4
Biological Activity: CDK5-IN-3 (compound 11) is a potent CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD)[1].
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CDK5-IN-3 | 99.49% | CDK5-IN-3 (compound 11) is a potent CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD). | ||||||||||||||||||||
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Keywords