2668297-70-7
2668297-70-7
Chemical Structure
ZDWX-25
- CAS No.: 2668297-70-7
- Formula:C17H15N3O3
- Molecular Weight:309.32
IUPAC Name: methyl 1-(cyclopropanecarboxamido)-9H-pyrido[3,4-b]indole-7-carboxylate
InChIKey: ACRYPFBNYMEDTL-UHFFFAOYSA-N
SMILES: COC(C1=CC=C2C(NC3=C(N=CC=C23)NC(C4CC4)=O)=C1)=O
Biological Activity: ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. ZDWX-25 possesses significant cytotoxic activities against SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for researching alzheimer's disease[1].
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ZDWX-25 | ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. ZDWX-25 possesses significant cytotoxic activities against SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for researching alzheimer's disease. | |||||||||||||||||||||
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References
Keywords
