2673270-28-3
2673270-28-3
Chemical Structure
TML-6-d3
- CAS No.: 2673270-28-3
- Formula:C30H34D3NO7
- Molecular Weight:526.64
IUPAC Name: (E)-6-(3,4-dimethoxyphenyl)-3-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-N,N-diethyl-3-(methyl-d3)-4-oxohex-5-enamide
InChIKey: UWVCYNXVZRDWSD-KTPQXUQXSA-N
SMILES: COC1=C(C=C(C=C1)/C=C/C(C(C([2H])([2H])[2H])(C(/C=C/C2=CC=C(C(OC)=C2)OC)=O)CC(N(CC)CC)=O)=O)OC
Biological Activity: TML-6-d3 is the deuterium labeled TML-6. TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-
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TML-6-d3 | TML-6-d3 is the deuterium labeled TML-6. TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti- | |||||||||||||||||||||
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TML-6 | 98.34% | TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-oxidative Nrf2 gene. TML-6 has the potential for Alzheimer’s disease (AD) research. | ||||||||||||||||||||
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