2735015-60-6
Chemical Structure
TTBK1-IN-1
- CAS No.: 2735015-60-6
- Formula:C18H19N5O2
- Molecular Weight:337.38
IUPAC Name: (S)-1-(1-(2-amino-6-methoxypyrimidin-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl)-3-methylpent-1-yn-3-ol
InChIKey: HPJVZSVEIGCFJP-SFHVURJKSA-N
SMILES: O[C@@](C)(CC)C#CC1=CC2=C(C=CN2C3=CC(OC)=NC(N)=N3)C=N1
Biological Activity: TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor with an IC50 of 2.7 nM. TTBK1-IN-1 can be used for the research of alzheimer’s disease and related tauopathies[1]. TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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TTBK1-IN-1 | 99.17% | TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor with an IC50 of 2.7 nM. TTBK1-IN-1 can be used for the research of alzheimer’s disease and related tauopathies. TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords
