2760328-82-1
2760328-82-1
Chemical Structure
IRAK1/4/pan-FLT3 Kinase-IN-1
- CAS No.: 2760328-82-1
- Formula:C21H26FN5O2
- Molecular Weight:399.46
InChIKey: SPZWEDSSAIAPRC-HOCLYGCPSA-N
SMILES: CC(O)(C1=CN2C(C=C1OC)=NC=C2C3=NC(N[C@H]4CNCC[C@@H]4F)=CC=C3)C
Biological Activity: IRAK1/4/pan-FLT3 Kinase-IN-1 is an orally active, potent and selective IRAK/pan-FLT3 kinase inhibitor with IC50s of 5 nM, 0.6 nM and <0.5 nM against IRAK1, IRAK4 and FLT3, respectively. IRAK1/4/pan-FLT3 Kinase-IN-1 can be used for research on AML[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IRAK1/4/pan-FLT3 Kinase-IN-1 | 99.25% | IRAK1/4/pan-FLT3 Kinase-IN-1 is an orally active, potent and selective IRAK/pan-FLT3 kinase inhibitor with IC50s of 5 nM, 0.6 nM and <0.5 nM against IRAK1, IRAK4 and FLT3, respectively. IRAK1/4/pan-FLT3 Kinase-IN-1 can be used for research on AML. | ||||||||||||||||||||
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References
Keywords
