2763208-56-4
Chemical Structure
STAT3-IN-33
- CAS No.: 2763208-56-4
- Formula:C21H21BrN4O4S
- Molecular Weight:505.38
IUPAC Name: (4-bromo-1,1-dioxidobenzo[b]thiophen-2-yl)(4-(3,5,6-trimethylpyrazine-2-carbonyl)piperazin-1-yl)methanone
InChIKey: LVQZKIIWVAUQQT-UHFFFAOYSA-N
SMILES: O=C(N1CCN(CC1)C(C2=CC3=C(S2(=O)=O)C=CC=C3Br)=O)C4=C(C)N=C(C)C(C)=N4
Biological Activity: STAT3-IN-33 (compound 7f) is a potent STAT3 inhibitor with anti-cancer activity. STAT3-IN-33 exhibits antiproliferative activity in HCT116, MCF-7, and MDA-MB-231 cells, with IC50s of 6.44, 3.29, and 4.86 μM, respectively. STAT3-IN-33 can be used for breast and colon cancer research[1].
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STAT3-IN-33 | STAT3-IN-33 (compound 7f) is a potent STAT3 inhibitor with anti-cancer activity. STAT3-IN-33 exhibits antiproliferative activity in HCT116, MCF-7, and MDA-MB-231 cells, with IC50s of 6.44, 3.29, and 4.86 μM, respectively. STAT3-IN-33 can be used for breast and colon cancer research. | |||||||||||||||||||||
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Keywords
