STAT3-IN-33
STAT3-IN-33 (compound 7f) is a potent STAT3 inhibitor with anti-cancer activity. STAT3-IN-33 exhibits antiproliferative activity in HCT116, MCF-7, and MDA-MB-231 cells, with IC50s of 6.44, 3.29, and 4.86 μM, respectively. STAT3-IN-33 can be used for breast and colon cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2763208-56-4
- Formula: C21H21BrN4O4S
- Molecular Weight:505.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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STAT3 |
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
6.44 μM
Compound: 108
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
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[PMID: 39955802] |
Chemical Information
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CAS No. 2763208-56-4
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Molecular Weight 505.38
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Formula C21H21BrN4O4S
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SMILES
O=C(N1CCN(CC1)C(C2=CC3=C(S2(=O)=O)C=CC=C3Br)=O)C4=C(C)N=C(C)C(C)=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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