2768099-51-8

KRAS G12C degrader-1 Chemical Structure
2768099-51-8

Chemical Structure

KRAS G12C degrader-1

  • CAS No.: 2768099-51-8
  • Formula:C63H75ClN14O6
  • Molecular Weight:1159.81

InChIKey: RKQABCMDWYZJBX-OLCJBLMYSA-N

SMILES: O=C(C=C)N1CCN(C2=NC(OC[C@H]3N(C)C[C@@H](N4CCN(C(C5CCN(CC6=CC=C(N7C(C(NCC)=O)=NN=C7C8=C(O)C=C(O)C(C(C)C)=C8)C=C6)CC5)=O)CC4)C3)=NC9=C2CCN(C%10=C(C(Cl)=CC=C%11)C%11=CC=C%10)C9)C[C@@H]1CC#N

Biological Activity: KRAS G12C degrader-1 (Compound 283) is a potent KRAS G12C degrader (DC50: < 100 nM) for cancer research. KRAS G12C degrader-1 is a chaperone (HSP90)-mediated protein degrader (CHAMPs)[1].

Cat. No. Product Name Purity Description Pricing
HY-153881
KRAS G12C degrader-1 KRAS G12C degrader-1 (Compound 283) is a potent KRAS G12C degrader (DC50: < 100 nM) for cancer research. KRAS G12C degrader-1 is a chaperone (HSP90)-mediated protein degrader (CHAMPs).
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