2768472-86-0
2768472-86-0
Chemical Structure
EGFR Ligand-Linker Conjugates 1
- CAS No.: 2768472-86-0
- Formula:C37H47N9O3
- Molecular Weight:665.83
SMILES: C=CC(N1CCC[C@@H](C1)N2C3=C(N=C2NC4=CC=CC=C4)C=NC(NC5=CC=C(C=C5)N6CCN(CC6)CCCCCCCC(O)=O)=N3)=O
Biological Activity: EGFR Ligand-Linker Conjugates 1 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for EGFR (HY-150905) and a PROTAC linker, which recruits E3 ligases. EGFR Ligand-Linker Conjugates 1 can be used for synthesis of PROTAC EGFR degrader 3 (HY-144605)[1].
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EGFR Ligand-Linker Conjugates 1 | EGFR Ligand-Linker Conjugates 1 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for EGFR (HY-150905) and a PROTAC linker, which recruits E3 ligases. EGFR Ligand-Linker Conjugates 1 can be used for synthesis of PROTAC EGFR degrader 3 (HY-144605). | |||||||||||||||||||||
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References
Keywords
