2770269-44-6
Chemical Structure
LRRK2-IN-8
- CAS No.: 2770269-44-6
- Formula:C16H12F2N6
- Molecular Weight:326.30
IUPAC Name: 9-(2,6-difluorophenyl)-7,8-dihydro-3H,6H-2,3,5,5a,8a,10-hexaazabenzo[cd]cyclopenta[h]azulene
InChIKey: NTLDJWYHDAANKC-UHFFFAOYSA-N
SMILES: FC1=CC=CC(F)=C1C2=NC3=C(C4=C(N2CCC5)N5N=C4)NN=C3
Biological Activity: LRRK2-IN-8 is a LRRK2 inhibitor. LRRK2-IN-8 inhibits LRRK2 (wt) and LRRK2 (G2019) with IC50s lower than 10 nM, and inhibits TYK2 and NUAK1 with IC50s of 10-100 nM[1].
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LRRK2-IN-8 | LRRK2-IN-8 is a LRRK2 inhibitor. LRRK2-IN-8 inhibits LRRK2 (wt) and LRRK2 (G2019) with IC50s lower than 10 nM, and inhibits TYK2 and NUAK1 with IC50s of 10-100 nM. | |||||||||||||||||||||
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Keywords