2770804-74-3
Chemical Structure
Topoisomerase I/II inhibitor 3
- CAS No.: 2770804-74-3
- Formula:C24H24N2O4
- Molecular Weight:404.46
IUPAC Name: 7-(6-(azepan-1-ylmethyl)benzo[d][1,3]dioxol-5-yl)-[1,3]dioxolo[4,5-h]isoquinoline
InChIKey: KGYHKHZROFSQOS-UHFFFAOYSA-N
SMILES: C1(C=CC2=C3C=NC(C4=CC5=C(OCO5)C=C4CN6CCCCCC6)=C2)=C3OCO1
Biological Activity: Topoisomerase I/II inhibitor 3 (compound 7) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 3 can inhibit cell proliferation, invasion and migration, and induce apoptosis by inhibiting PI3K/Akt/mTOR signaling pathway. Topoisomerase I/II inhibitor 3 can be used for liver cancer research[1].
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Topoisomerase I/II inhibitor 3 | Topoisomerase I/II inhibitor 3 (compound 7) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 3 can inhibit cell proliferation, invasion and migration, and induce apoptosis by inhibiting PI3K/Akt/mTOR signaling pathway. Topoisomerase I/II inhibitor 3 can be used for liver cancer research. | |||||||||||||||||||||
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Keywords
