2846077-70-9
Chemical Structure
D4R antagonis-2
- CAS No.: 2846077-70-9
- Formula:C21H23ClF2N2O2
- Molecular Weight:408.87
IUPAC Name: N-(3-chloro-2-methylphenyl)-2-(4-((3,4-difluorobenzyl)oxy)piperidin-1-yl)acetamide
InChIKey: NXHYXFTYHKKMBV-UHFFFAOYSA-N
SMILES: CC1=C(C=CC=C1NC(CN2CCC(CC2)OCC3=CC=C(C(F)=C3)F)=O)Cl
Biological Activity: D4R antagonist-2 is a potent and selective D4R antagonist with an IC50 of 6.52 µM. D4R antagonist-2 displays very favorable in vitro PK parameters and has good brain penetration. D4R antagonist-2 has the potential for the research of Parkinson’s disease[1].
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D4R antagonis-2 | D4R antagonist-2 is a potent and selective D4R antagonist with an IC50 of 6.52 µM. D4R antagonist-2 displays very favorable in vitro PK parameters and has good brain penetration. D4R antagonist-2 has the potential for the research of Parkinson’s disease. | |||||||||||||||||||||
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Keywords