2847838-67-7
2847838-67-7
Chemical Structure
sEH/HDAC6-IN-1
- CAS No.: 2847838-67-7
- Formula:C27H40N4O4
- Molecular Weight:484.63
InChIKey: LICDGBVIDDVNJZ-IIEILYMYSA-N
SMILES: O=C(NC(C=C1)=CC=C1C(NCCCCCCC(NO)=O)=O)N[C@@](C[C@]2(C3)C)(C[C@H]3C4)C[C@]4(C2)C
Biological Activity: sEH/HDAC6-IN-1 (compound M9) is a selective, orally active dual inhibitor for sEH and HDAC6, with IC50s of 2 nM, 0.72 nM and 5 nM, for human sEH, murine sEH and HDAC6, respectively. sEH/HDAC6-IN-1 reveals analgesic and anti-inflammatory effects[1].
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sEH/HDAC6-IN-1 | sEH/HDAC6-IN-1 (compound M9) is a selective, orally active dual inhibitor for sEH and HDAC6, with IC50s of 2 nM, 0.72 nM and 5 nM, for human sEH, murine sEH and HDAC6, respectively. sEH/HDAC6-IN-1 reveals analgesic and anti-inflammatory effects. | |||||||||||||||||||||
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References
Keywords
