2851012-65-0
2851012-65-0
Chemical Structure
MAO-B-IN-7
- CAS No.: 2851012-65-0
- Formula:C25H31NO4
- Molecular Weight:409.52
IUPAC Name: 3-butyl-6-((3-hydroxy-4-(piperidin-1-ylmethyl)benzyl)oxy)isobenzofuran-1(3H)-one
InChIKey: KAFBBPBROARMRS-UHFFFAOYSA-N
SMILES: CCCCC1OC(C2=CC(OCC3=CC(O)=C(C=C3)CN4CCCCC4)=CC=C21)=O
Biological Activity: MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor with IC50s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 can effectively alleviate oxidative stress and neuroinflammatory damage[1].
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MAO-B-IN-7 | MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor with IC50s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 can effectively alleviate oxidative stress and neuroinflammatory damage. | |||||||||||||||||||||
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References
Keywords
