2918813-56-4
Chemical Structure
E3 Ligase Ligand-linker Conjugate 50
- CAS No.: 2918813-56-4
- Formula:C33H47N5O6S
- Molecular Weight:641.82
InChIKey: UUYHXXHEFKXGFH-CMTIAEDTSA-N
SMILES: O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)(C)C)NC(C2CCN(CC2)C(OC(C)(C)C)=O)=O)=O)NCC(C=C3)=CC=C3C(SC=N4)=C4C
Biological Activity: E3 Ligase Ligand-linker Conjugate 50 is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. E3 Ligase Ligand-linker Conjugate 50 can be used as a key intermediate for the synthesis of complete PROTAC molecules.
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E3 Ligase Ligand-linker Conjugate 50 | E3 Ligase Ligand-linker Conjugate 50 is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. E3 Ligase Ligand-linker Conjugate 50 can be used as a key intermediate for the synthesis of complete PROTAC molecules. | |||||||||||||||||||||
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Keywords
