2923879-23-4
Chemical Structure
AMXI-5001 hydrochloride
- CAS No.: 2923879-23-4
- Formula:C25H21ClFN5O3
- Molecular Weight:493.92
IUPAC Name: (6-amino-5-methylpyridin-3-yl)methanol
InChIKey: DCTVJMPYKWHEFD-UHFFFAOYSA-N
SMILES: [H]Cl.O=C(NC1=NC2=C(N1)C=C(C3=C(F)C=CC(CC4=NNC(C5=C4C=CC=C5)=O)=C3)C=C2)OCC
Biological Activity: AMXI-5001 hydrochloride is a potent, orally active, and dual parp1/2 and microtubule polymerization inhibitor. MXI-5001 hydrochloride exhibits selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC50s than existing clinical PARP1/2 inhibitors. AMXI-5001 hydrochloride induces complete regression of established tumors, including exceedingly large tumors[1].
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AMXI-5001 hydrochloride | 98.05% | AMXI-5001 hydrochloride is a potent, orally active, and dual parp1/2 and microtubule polymerization inhibitor. MXI-5001 hydrochloride exhibits selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC50s than existing clinical PARP1/2 inhibitors. AMXI-5001 hydrochloride induces complete regression of established tumors, including exceedingly large tumors. | ||||||||||||||||||||
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Keywords
