3016304-64-3
3016304-64-3
Chemical Structure
RIPK1-IN-21
- CAS No.: 3016304-64-3
- Formula:C17H14F2N4O
- Molecular Weight:328.32
InChIKey: VAJYDZXWUQIBAA-IGEOTXOUSA-N
SMILES: O=C1N(C2(C3)CC3(C#N)C2)N=C4N1[C@@H](CC4)C5=CC(F)=CC(F)=C5
Biological Activity: RIPK1-IN-21 (Compound I-5) is an inhibitor of RIPK1 with an EC50 value of 14.8 nM. RIPK1-IN-21 can be used in the research of neurodegenerative, autoimmune, and inflammatory diseases[1].
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RIPK1-IN-21 | RIPK1-IN-21 (Compound I-5) is an inhibitor of RIPK1 with an EC50 value of 14.8 nM. RIPK1-IN-21 can be used in the research of neurodegenerative, autoimmune, and inflammatory diseases. | |||||||||||||||||||||
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References
- [1]. Sabnis R W. Novel Fused Triazole Compounds as RIPK1 Inhibitors for Treating Neurodegenerative, AutoimmSabnis R W. Novel Fused Triazole Compounds as RIPK1 Inhibitors for Treating Neurodegenerative, Autoimmune, and Inflammatory Diseases[J]. ACS Medicinal Chemistry Letters, 2024.une, and Inflammatory Diseases[J]. ACS Medicinal Chemistry Letters, 2024. [Content Brief]
Keywords
