RIPK1-IN-21
RIPK1-IN-21 (Compound I-5) is an inhibitor of RIPK1 with an EC50 value of 14.8 nM. RIPK1-IN-21 can be used in the research of neurodegenerative, autoimmune, and inflammatory diseases.
For research use only. We do not sell to patients.
- CAS No.: 3016304-64-3
- Formula: C17H14F2N4O
- Molecular Weight:328.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
EC50: 14.8 nM (RIPK1)[1].
Chemical Information
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CAS No. 3016304-64-3
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Molecular Weight 328.32
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Formula C17H14F2N4O
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SMILES
O=C1N(C2(C3)CC3(C#N)C2)N=C4N1[C@@H](CC4)C5=CC(F)=CC(F)=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sabnis R W. Novel Fused Triazole Compounds as RIPK1 Inhibitors for Treating Neurodegenerative, AutoimmSabnis R W. Novel Fused Triazole Compounds as RIPK1 Inhibitors for Treating Neurodegenerative, Autoimmune, and Inflammatory Diseases[J]. ACS Medicinal Chemistry Letters, 2024.une, and Inflammatory Diseases[J]. ACS Medicinal Chemistry Letters, 2024. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)