3021581-79-0
3021581-79-0
Chemical Structure
Abd110
- CAS No.: 3021581-79-0
- Formula:C41H42N8O7S
- Molecular Weight:790.89
InChIKey: HPPMEDDOFPWBEG-UHFFFAOYSA-N
SMILES: O=C(C1=NC(C2=CC=C(S(=O)(NCCCCCC(NCCCC#CC3=CC=CC4=C3CN(C(CC5)C(NC5=O)=O)C4=O)=O)=O)C=C2)=CN=C1N)NC6=CC=CC=C6
Biological Activity: Abd110 is a selective ATR PROTAC degrader. Abd110 recruits Cereblon to induce the proteasomal degradation of ATR, and reduces the levels of phosphorylated ATR and downstream phosphorylated CHK1. Abd110 can be used for research on pancreatic cancer and cervical cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Abd110 | 98.67% | Abd110 is a selective ATR PROTAC degrader. Abd110 recruits Cereblon to induce the proteasomal degradation of ATR, and reduces the levels of phosphorylated ATR and downstream phosphorylated CHK1. Abd110 can be used for research on pancreatic cancer and cervical cancer. | ||||||||||||||||||||
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