3029584-84-4
Chemical Structure
BSc5367
- CAS No.: 3029584-84-4
- Formula:C20H15N3O2
- Molecular Weight:329.35
IUPAC Name: methyl 3-(3-(pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzoate
InChIKey: GZHRICWZECSYJT-UHFFFAOYSA-N
SMILES: COC(C1=CC(C2=CN=C3NC=C(C3=C2)C4=CN=CC=C4)=CC=C1)=O
Biological Activity: BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM. NIMA-related protein kinase Nek1 is crucially involved in cell cycle regulation, DNA repair and microtubule regulation and dysfunctions of Nek1 play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BSc5367 | 98.21% | BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM. NIMA-related protein kinase Nek1 is crucially involved in cell cycle regulation, DNA repair and microtubule regulation and dysfunctions of Nek1 play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer. | ||||||||||||||||||||
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Keywords
