3037413-54-7

NEK7 degrader-2 Chemical Structure
3037413-54-7

Chemical Structure

NEK7 degrader-2

  • CAS No.: 3037413-54-7
  • Formula:C19H23N3O3
  • Molecular Weight:341.40

SMILES: O=C1NC(C(CC1)N2C(C3=CC=C(C4NCCCC4)C=C3C2C)=O)=O

Biological Activity: NEK7 degrader-2 (Compound 25) is a NEK7 degrader. NEK7 degrader-2 shows dose-dependent NEK7 degradation ability in human PBMC-derived macrophages. NEK7 degrader-2 reduce the release level of pro-inflammatory cytokines IL-1β induced by NLRP3 inflammasome activation. NEK7 degrader-2 can be used for the study of inflammatory diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-177559 		NEK7 degrader-2 NEK7 degrader-2 (Compound 25) is a NEK7 degrader. NEK7 degrader-2 shows dose-dependent NEK7 degradation ability in human PBMC-derived macrophages. NEK7 degrader-2 reduce the release level of pro-inflammatory cytokines IL-1β induced by NLRP3 inflammasome activation. NEK7 degrader-2 can be used for the study of inflammatory diseases.
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