3037516-37-0
3037516-37-0
Chemical Structure
MAO-B-IN-4
- CAS No.: 3037516-37-0
- Formula:C23H20ClF2N3
- Molecular Weight:411.87
IUPAC Name: N-(1-acetylindolin-5-yl)-5-cyclopropyl-2-methoxybenzenesulfonamide
InChIKey: PKKVQHSSLZVNAS-UHFFFAOYSA-N
SMILES: FC1(CCN(CC1)C2=NC3=CC=CC=C3C4=C2C=CN4CC5=CC(Cl)=CC=C5)F
Biological Activity: MAO-B-IN-4 (Compound 26) is an orally active and reversible MAO-B inhibitor with an IC50 of 9 nM. MAO-B-IN-4 has good metabolic stability, safety profile and brain permeability. MAO-B-IN-4 shows antidepressant activity in rats and mice. MAO-B-IN-4 can be used in studies related to Alzheimer's disease[1].
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MAO-B-IN-4 | MAO-B-IN-4 (Compound 26) is an orally active and reversible MAO-B inhibitor with an IC50 of 9 nM. MAO-B-IN-4 has good metabolic stability, safety profile and brain permeability. MAO-B-IN-4 shows antidepressant activity in rats and mice. MAO-B-IN-4 can be used in studies related to Alzheimer's disease. | |||||||||||||||||||||
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References
Keywords
