3037664-05-1
Chemical Structure
Trypanothione synthetase-IN-5
- CAS No.: 3037664-05-1
- Formula:C35H39F2IN4O3
- Molecular Weight:728.61
InChIKey: VNRJLUHEWLUDDK-UHFFFAOYSA-N
SMILES: O=C(N1CC[N+](C)(CC1)CCCC2=CC=CC=C2)N(CC3=CC=C(O3)C(NCCC4=CC=C(C=C4)F)=O)C5=CC=C(C=C5)F.[I-]
Biological Activity: Trypanothione synthetase-IN-5 (compound 9) is a trypanothione reductase (TR) inhibitor, with an IC50 of 20.5 μM for Leishmania infantum TR. Trypanothione synthetase-IN-5 also has inhibitory activity for human glutathione reductase (hGR), with an IC50 of 62.4 μM[1].
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Trypanothione synthetase-IN-5 | Trypanothione synthetase-IN-5 (compound 9) is a trypanothione reductase (TR) inhibitor, with an IC50 of 20.5 μM for Leishmania infantum TR. Trypanothione synthetase-IN-5 also has inhibitory activity for human glutathione reductase (hGR), with an IC50 of 62.4 μM. | |||||||||||||||||||||
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Keywords