3051509-32-8
3051509-32-8
Chemical Structure
URAT1/GLUT9-IN-2
- CAS No.: 3051509-32-8
- Formula:C25H21N3O5S
- Molecular Weight:475.52
InChIKey: LJSASFYIZSIJLR-UHFFFAOYSA-N
SMILES: O=C(NS(=O)(C1=CC=CC([N+]([O-])=O)=C1)=O)C2=CC=CN2CC3=C4C=CC=CC4=C(C=C3)C5CC5
Biological Activity: URAT1/GLUT9-IN-2 is a selective, orally active URAT1/GLUT9 inhibitor, with an IC50 of 2.81 μM against URAT1 and an IC50 of 12.53 μM against GLUT9. URAT1/GLUT9-IN-2 reduces serum uric acid levels and protects renal function. URAT1/GLUT9-IN-2 can be used in research related to hyperuricemia and hyperuricemic nephropathy[1].
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URAT1/GLUT9-IN-2 | URAT1/GLUT9-IN-2 is a selective, orally active URAT1/GLUT9 inhibitor, with an IC50 of 2.81 μM against URAT1 and an IC50 of 12.53 μM against GLUT9. URAT1/GLUT9-IN-2 reduces serum uric acid levels and protects renal function. URAT1/GLUT9-IN-2 can be used in research related to hyperuricemia and hyperuricemic nephropathy. | |||||||||||||||||||||
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References
Keywords
