3051828-81-7
3051828-81-7
Chemical Structure
PI3Kδ-IN-23
- CAS No.: 3051828-81-7
- Formula:C30H30N6O5
- Molecular Weight:554.60
InChIKey: IKONUSTXITZHRM-NRFANRHFSA-N
SMILES: O=C(OC1=CC=CC=C1)C2=CC(C3=NC(C(N[C@@H]4CN(CC4)C(C5CCOCC5)=O)=NC=N6)=C6C=C3)=CN=C2OC
Biological Activity: PI3Kδ-IN-23 (compound A11) is a potent inhibitor of PI3Kδ, with the IC50 of 0.27 nM. PI3Kδ-IN-23 bounds to PI3Kδ by covalent-bonding interactions with Lys779. PI3Kδ-IN-23 plays an important role in cancer research[1].
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PI3Kδ-IN-23 | PI3Kδ-IN-23 (compound A11) is a potent inhibitor of PI3Kδ, with the IC50 of 0.27 nM. PI3Kδ-IN-23 bounds to PI3Kδ by covalent-bonding interactions with Lys779. PI3Kδ-IN-23 plays an important role in cancer research. | |||||||||||||||||||||
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References
Keywords
