PI3Kδ-IN-23
PI3Kδ-IN-23 (compound A11) is a potent inhibitor of PI3Kδ, with the IC50 of 0.27 nM. PI3Kδ-IN-23 bounds to PI3Kδ by covalent-bonding interactions with Lys779. PI3Kδ-IN-23 plays an important role in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3051828-81-7
- Formula: C30H30N6O5
- Molecular Weight:554.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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PI3Kδ 0.27 nM (IC50) |
Chemical Information
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CAS No. 3051828-81-7
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Molecular Weight 554.60
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Formula C30H30N6O5
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SMILES
O=C(OC1=CC=CC=C1)C2=CC(C3=NC(C(N[C@@H]4CN(CC4)C(C5CCOCC5)=O)=NC=N6)=C6C=C3)=CN=C2OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PI3Kδ-IN-23 Related Classifications
HY-169983 Related Classifications
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