3066143-73-2

HDAC1-IN-8 Chemical Structure
3066143-73-2

Chemical Structure

HDAC1-IN-8

  • CAS No.: 3066143-73-2
  • Formula:C22H24N2O4
  • Molecular Weight:380.44

SMILES: O=C(NO)CCCCCOC1=CC(C=C2)=C(C=C1)N=C2C3=CC=C(OC)C=C3

Biological Activity: HDAC1-IN-8 (compound 5c) is a potent and selective HDAC1 inhibitor with IC50 values of 11.94, 22.95, >500 µM for HDAC1, HDAC6, HDAC8, respectively. HDAC1-IN-8 shows antiproliferative activity. HDAC1-IN-8 induces cell cycle arrest at G1 and G2/M. HDAC1-IN-8 induces autophagy. HDAC1-IN-8 shows anticancer activity and has the potential for the research of lung cancer[1].

Cat. No. Product Name Purity Description Pricing
HY-168477 		HDAC1-IN-8 HDAC1-IN-8 (compound 5c) is a potent and selective HDAC1 inhibitor with IC50 values of 11.94, 22.95, >500 µM for HDAC1, HDAC6, HDAC8, respectively. HDAC1-IN-8 shows antiproliferative activity. HDAC1-IN-8 induces cell cycle arrest at G1 and G2/M. HDAC1-IN-8 induces autophagy. HDAC1-IN-8 shows anticancer activity and has the potential for the research of lung cancer.
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