3081937-95-0
3081937-95-0
Chemical Structure
SJ45566
- CAS No.: 3081937-95-0
- Formula:C37H42ClN9O3S
- Molecular Weight:728.31
InChIKey: BYPUUWWNEKQLNS-UHFFFAOYSA-N
SMILES: O=C(NC1=C(Cl)C=CC=C1C)C(S2)=CN=C2NC3=CC(N4CCC(CN5CCN(C6=CC=C(C7CCC(NC7=O)=O)C=C6)CC5)CC4)=NC(C)=N3
Biological Activity: SJ45566 a potent and orally active PROTAC-based LCK degrader, with a DC50 of 1.21 nM. SJ45566 can be used in the research for T‑Cell Acute Lymphoblastic Leukemia[1].
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SJ45566 | 98.41% | SJ45566 a potent and orally active PROTAC-based LCK degrader, with a DC50 of 1.21 nM. SJ45566 can be used in the research for T‑Cell Acute Lymphoblastic Leukemia. | ||||||||||||||||||||
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References
Keywords
